TIME-COURSE SWRNA-SEQ UNCOVERS A HIERARCHICAL GENE REGULATORY NETWORK IN CONTROLLING THE RESPONSE-REPAIR-REMODELING AFTER WOUNDING

Time-course swRNA-seq uncovers a hierarchical gene regulatory network in controlling the response-repair-remodeling after wounding

Abstract Wounding initiates intricate responses crucial for tissue repair and regeneration.Yet, the gene regulatory networks governing wound healing remain poorly understood.Here, employing single-worm RNA sequencing (swRNA-seq) across 12 time-points, we delineated a three-stage wound repair process in C.elegans: response, repair, and remodeling.In

read more




Immunostimulation of Asian elephant (Elephas maximus) blood cells by parapoxvirus ovis and CpG motif-containing bacterial plasmid DNA upregulates innate immune gene expression

The immune system of Asian elephants (Elephas maximus) is poorly studied, compared to that of livestock, rodents or humans.The innate immune response has Loft Bed become a focus of interest in relation to Elephant endotheliotropic herpesviruses (EEHVs).EEHVs cause a fatal hemorrhagic disease (EEHV-HD) and are a significant threat to captive Asian e

read more